Use the eco-friendly wipe in the same way as you would with the calming spray by gentle rubbing around muzzle, under chin and top of chest of your pet (including horses!).
Or you can rub on your fingers before handling an anxious pet.
It can be used to wipe down surfaces such as an examination or grooming bench top.
You can also tie to a cat basket when travelling to a vet or place on bedding in home and car!